The first rope replacement of shaft hoisting system is a key construction work with heavy workload,difficult working conditions and high risk in the management of shaft hoisting system. The traditional first rope replacement operation usually takes 3~5 days, while the interactive fast rope replacement only takes 8~10 hours. This paper introduces the application and key points of interactive fast rope replacement based on the replacement of head rope and suspension device of hoisting 2 system in main shaft of Xiaozhuang coal mine, so as to further improve the efficiency of rope replacement in Xiaozhuang coal mine.