Abstract: During the pile foundation construction of the new bridge of Guanhua Avenue, there are some technical problems, such as karst cave, slurry leakage and hole collapse during drilling,hammer sticking and hammer dropping, and underwater concrete pouring loss. During the construction, slurry filling, yellow clay rubble backfilling, steel casing follow-up, automatic punching electronic control equipment, increasing the buried depth of conduit, increasing the initial stock of concrete, embedding steel casing and other measures were adopted to reduce the sticking Accidents such as hammer dropping and underwater concrete pouring loss ensure the quality, progress and safety of pile foundation construction.