Abstract: Subway is the top priority of urban construction, which is directly related to the efficiency and level of urban public transport. At the same time, subway is also an important index to measure the strength of a city. But the subway needs to consume a lot of electric energy in the process of operation, among them, the ventilation and air conditioning system consumes the highest power, it can reach 50% of the total energy consumption of subway every year, therefore, energy saving and consumption reduction of subway ventilation and air conditioning system is very important for subway transportation. Based on this, this paper analyzes the composition of subway ventilation and air conditioning system, the application of intelligent control system of ventilation and air conditioning system is further explored, for reference.