Abstract: With the continuous development of high-rise buildings, the problem of fire hazards in high-rise buildings is becoming more and more serious. In order to prevent huge losses from fires in high-rise buildings, at present our country needs to strengthen fire protection supervision, by formulating a sound fire prevention system, comprehensively carry out fire inspection, solve the current problems of blocked fire passages in highrise buildings, unqualified fire-fighting facilities and shortage of fire early warning system. Based on this, this paper discusses the fire characteristics of high-rise buildings, this paper analyzes the current situation of fire prevention supervision and inspection of urban high-rise buildings, the countermeasures to improve the effectiveness of fire prevention supervision and inspection of urban high-rise buildings are studied.