Abstract: With the continuous improvement of the level of urbanization and industrialization in China, the shortage of fresh water resources is becoming increasingly scarce. This has become a bottleneck restricting the development of urbanization in China. Desalination of seawater has become an important choice for coastal cities to solve such problems. Valves are widely used in seawater desalination plants. As an important control component in each process,their selection and application are particularly important. This article takes a 100,000-ton desalination plant in Qingdao as an example to deeply analyze various valves in the seawater desalination process The selection basis and application process in the process, and put forward corresponding solutions to the problems.