Abstract: This article analyzes and elaborates on the expansion project of the Occupational Disease Complex of the Second Hospital of Huangshi City from the aspects of design conception, planning layout, road organization, single design, etc., and proposes to address irregular terrain, large site elevation, and surrounding restrictions Under many adverse circumstances, make full use of site characteristics, borrow environmental resources, and design methods tailored to local conditions in order to create a modern, comfortable and efficient medical environment for users.